Simplify your product dev with Clearly Soluble™ Water Soluble CBD & CBDA

Simplify your product dev with Clearly Soluble™ Water Soluble CBD & CBDA

Clearly Soluble™ is a water soluble powdered cannabinoid product based on beta‐cyclodextrin (β-CD). VFS Labs manufacturers Clearly Soluble in three varieties: CBD, CBDA, and a 50/50 mix of CBD + CBDA. By combining a molecule of CBD or CBDA with a molecule of β-CD, it creates an inclusion complex. In essence, a hydrophobic molecule such as CBD or CBDA is dissolved in the oleophilic center or “cup” of β-CD, a cyclic sugar (cycloheptaamylose), forming a supramolecular complex, as shown below in Figure 1.

Clearly Soluble CBD / CBDA Inclusion Complex

Clearly Soluble™ is produced using a proprietary, patent pending, water‐based process. No other solvent is used in the process. The CBD product is formed by decarboxylation of CBDA in situ. The CBDA product is formed in a 1:1 ratio of CBDA to β-CD, also proprietary. The CBD powder will have a potency of ~18% by weight and the CBDA product will be ~20%.

The advantages of Clearly Soluble CBD and CBDA powders are:

  • free‐flowing.
  • compatible and easily mixed with most dry ingredients.
  • very stable with a shelf life of at least one year.
  • easier to handle than tinctures or distillates.

What CBD products would be a good fit for Clearly Soluble?
Water soluble powders are extremely stable and flowable, simplifying the infusion process. No more tinctures or “goo” to deal with.

The typical daily dosage for CBDA is 5 to 20 milligrams. For a complex that is 20% CBDA by weight, the typical dosage of the ingredient (complex) would thus be 25 to 100 milligrams per day, per adult. Taking into account how often a product will be consumed per day will allow the formulator to determine how much powder is needed per dose.

Gel Caps and Nutraceuticals: Clearly Soluble powders mix well with typical dry diluents and excipients. For ease of handling, the water soluble powder may be diluted with pure β‐cyclodextrin, powdered sugars or other excipients.

Gum, Chocolate and Confectioneries: Water soluble CBD and CBDA are extremely temperature-stable and can be added to confectioneries just like you’d use powdered sugar. When infusing water soluble CBDA into products that require the use of high heat, it would be preferable to add the powder at the latest possible moment in the production process. Clearly Soluble CBD powder is the most heat‐tolerant.

Honey and Syrups: Because Clearly Soluble powder is based upon a cyclic sugar it is readily soluble in honey and syrups.

Drink Sweeteners: Natural or artificial sweeteners would pair well with Clearly Soluble.

Dry Food Mixes: The ingredients used for brownie or cake mix are compatible with water soluble powder and can easily be mixed into a stable dry product.

Water‐based Beverages: Clearly Soluble can easily be infused into water-based beverages ‐ like beer. Keep in mind that dosing concentrates above the solubility of the powder will become a dispersion. When the concentrate is added to a final product, the dilution will be such that the CBD or CBDA will then be completely soluble. It is unclear if the powder would survive fermentation (cyclic sugar) so we recommend adding it post‐fermentation.

Powdered Drink Mixes and Flavorings: Clearly Soluble mixes well with most powdered drink and flavoring formulations.

And SO many more…

TRY IT NOW! For a FREE SAMPLE of Clearly Soluble CBD or CBDA, please contact us and let us know where to send it. We’d love to hear how you are planning to use it too! We look forward to hearing from you!

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