Clearly Soluble™ is a water soluble powdered cannabinoid product based on beta‐cyclodextrin (β-CD). VFS Labs manufacturers Clearly Soluble in three varieties: CBD, CBDA, and a 50/50 mix of CBD + CBDA. By combining a molecule of CBD or CBDA with a molecule of β-CD, it creates an inclusion complex. In essence, a hydrophobic molecule such […]

CBDA Isolate Stability Microcrystalline Powder Contrary to common literature statements that CBDA is very unstable we have proven quite the opposite! Cannabidiolic acid (CBDA), in a low energy state, such as a microcrystalline powder or cyclodextrin inclusion complex, easily has a room temperature shelf life in excess of a year! CBDA is less stable in […]

There is a plethora of misconception about CBD and water solubility. Practically every hemp processing lab touts a “water soluble” version of CBD. To get to the root of the issue one must ask the question: Is it a dispersion, colloid or solution? Is the CBD actually made soluble? Is the description of the actual […]

Bioavailability is a subset of absorption. It is the percentage of an administered dose that reaches systemic circulation. Therefore, by definition, when a drug is administered intravenously, its bioavailability is 100% as 100% reaches blood circulation. Generally speaking, a drug’s oral bioavailability is the percentage of the drug dosage that eventually reaches circulation and the […]